Structural rearrangements in the C-terminal domain homolog of Orange Carotenoid Protein are crucial for carotenoid transfer

Dvir Harris , Adjele Wilson , Fernando Muzzopappa (1, 2) , Nikolai N. Sluchanko , Thomas Friedrich , Eugene G. Maksimov , Diana Kirilovsky (1, 2) , Noam Adir

1 I2BC - Institut de Biologie Intégrative de la Cellule
2 MROP - Mécanismes régulateurs chez les organismes photosynthétiques

Dvir Harris et al. present the structure of a homolog of the orange carotenoid protein (OCP) C-terminal domain, elaborating on this protein family’s carotenoid transfer mechanism. They observed major structural shifts in the homolog compared to that of the OCP C-terminal domain, with a strong positive impact on carotenoid uptake and delivery.

Domaines: Sciences du Vivant [q-bio]

Dvir Harris, Adjele Wilson, Fernando Muzzopappa, Nikolai N. Sluchanko, Thomas Friedrich, et al.. Structural rearrangements in the C-terminal domain homolog of Orange Carotenoid Protein are crucial for carotenoid transfer. Communications Biology, 2018, 1 (1), pp.1--11. ⟨10.1038/s42003-018-0132-5⟩. ⟨hal-02323108⟩