The configuration space of homologous proteins: A theoretical and practical framework to reduce the diversity of the protein sequence space after massive all-by-all sequence comparisons

Olivier Bastien (1) , Philippe Ortet (2) , Sylvaine Roy (3) , Eric Maréchal (1)

1 LPCV - Laboratoire de physiologie cellulaire végétale
2 PPV - Protéines de Protection des Végétaux
3 LBIM - Laboratoire Biologie-Informatique-Mathématique

Mots clés: statistical model; phylogenetic clusters; TULIP tree; Z-value; configuration space of homologous protein; sequence comparison; protein

Domaines: Biochimie, Biologie Moléculaire

Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eric Maréchal. The configuration space of homologous proteins: A theoretical and practical framework to reduce the diversity of the protein sequence space after massive all-by-all sequence comparisons. Future Generation Computer Systems, 2007, 23, pp.410-427. ⟨10.1016/j.future.2006.07.016⟩. ⟨hal-00121028⟩