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Fricke-Xylenol orange-Gelatin gel characterization with dual wavelength cone-beam optical CT scanner for applications in stereotactic and dynamic radiotherapy

Alice Rousseau 1 Christel Stien 1 Jean-Marc Bordy 1 Valentin Blideanu 1 
1 LNHB - Laboratoire National Henri Becquerel
DM2I - Département Métrologie Instrumentation & Information : DRT/LIST/DM2I
Abstract : Purpose: This study is about the development of a new dual wavelength reading method of Fricke-Xylenol orange-Gelatin (FXG) gel dosimeters on the Vista16™ optical Computed Tomography (CT) scanner to perform 3D dose distribution measurements in stereotactic and dynamic radiotherapy treatments. Methods: The dosimetric characteristics of an optimized FXG gel composition and its optical CT readout have been evaluated. A dual wavelength reading method has been developed on the CT scanner at wavelengths 590 nm and 633 nm. Small-field dose profile measurements with FXG gel and microDiamond (PTW) detectors were compared by γ-index analysis (0.5%/0.5mm) to validate this method. Results: This new reading method exhibits linear calibration curves in the 0 - 4 Gy and 2 - 10 Gy dose ranges at 590 nm and 633 nm respectively. The absorbed dose values under 4 Gy, measured at 590 nm, and those above 4 Gy, measured at 633 nm, are combined to plot a complete profile. A γ passing rate of 93.4 % was achieved. Conclusions: The new reading method of FXG gel dosimeters has been successfully implemented on the Vista16™ scanner to span absorbed doses representative of stereotactic and dynamic radiotherapy treatments and enable 3D measurements in tumor volumes and surrounding healthy tissues. Small-field profile measurements validated this reading method as FXG gel dosimeters and microDiamond detectors were in very close agreement. This dosimetric method is a promising candidate for 3D quality assurance end-to-end tests in stereotactic and dynamic radiotherapy.
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https://hal-cea.archives-ouvertes.fr/cea-03630980
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Submitted on : Tuesday, April 5, 2022 - 1:00:14 PM
Last modification on : Thursday, April 7, 2022 - 3:25:23 AM
Long-term archiving on: : Wednesday, July 6, 2022 - 6:49:19 PM

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Alice Rousseau, Christel Stien, Jean-Marc Bordy, Valentin Blideanu. Fricke-Xylenol orange-Gelatin gel characterization with dual wavelength cone-beam optical CT scanner for applications in stereotactic and dynamic radiotherapy. Physica Medica, Elsevier, 2022, 97, pp.1-12. ⟨10.1016/j.ejmp.2022.03.008⟩. ⟨cea-03630980⟩

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