Fricke-Xylenol orange-Gelatin gel characterization with dual wavelength cone-beam optical CT scanner for applications in stereotactic and dynamic radiotherapy - Archive ouverte HAL Access content directly
Journal Articles Physica Medica Year : 2022

Fricke-Xylenol orange-Gelatin gel characterization with dual wavelength cone-beam optical CT scanner for applications in stereotactic and dynamic radiotherapy

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Abstract

Purpose: This study is about the development of a new dual wavelength reading method of Fricke-Xylenol orange-Gelatin (FXG) gel dosimeters on the Vista16™ optical Computed Tomography (CT) scanner to perform 3D dose distribution measurements in stereotactic and dynamic radiotherapy treatments. Methods: The dosimetric characteristics of an optimized FXG gel composition and its optical CT readout have been evaluated. A dual wavelength reading method has been developed on the CT scanner at wavelengths 590 nm and 633 nm. Small-field dose profile measurements with FXG gel and microDiamond (PTW) detectors were compared by γ-index analysis (0.5%/0.5mm) to validate this method. Results: This new reading method exhibits linear calibration curves in the 0 - 4 Gy and 2 - 10 Gy dose ranges at 590 nm and 633 nm respectively. The absorbed dose values under 4 Gy, measured at 590 nm, and those above 4 Gy, measured at 633 nm, are combined to plot a complete profile. A γ passing rate of 93.4 % was achieved. Conclusions: The new reading method of FXG gel dosimeters has been successfully implemented on the Vista16™ scanner to span absorbed doses representative of stereotactic and dynamic radiotherapy treatments and enable 3D measurements in tumor volumes and surrounding healthy tissues. Small-field profile measurements validated this reading method as FXG gel dosimeters and microDiamond detectors were in very close agreement. This dosimetric method is a promising candidate for 3D quality assurance end-to-end tests in stereotactic and dynamic radiotherapy.
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cea-03630980 , version 1 (05-04-2022)

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Alice Rousseau, Christel Stien, Jean-Marc Bordy, Valentin Blideanu. Fricke-Xylenol orange-Gelatin gel characterization with dual wavelength cone-beam optical CT scanner for applications in stereotactic and dynamic radiotherapy. Physica Medica, 2022, 97, pp.1-12. ⟨10.1016/j.ejmp.2022.03.008⟩. ⟨cea-03630980⟩
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