Selective Actuation and Tomographic Imaging of Swarming Magnetite Nanoparticles - Archive ouverte HAL Access content directly
Journal Articles ACS Applied Nano Materials Year : 2021

Selective Actuation and Tomographic Imaging of Swarming Magnetite Nanoparticles

(1) , (2) , (2) , (1) , (3) , (2) , (1, 4)
1
2
3
4

Abstract

Micro- and nanomotors have seen substantial progress in recent years for biomedical applications. However, three grand challenges remain: (i) high velocities to overcome the blood flow, (ii) spatially selective control to enable complex navigation, and (iii) integration of a medical, tomographic real-time imaging method to acquire feedback information. Here, we report the combination of active magnetic matter and a medical imaging technique, namely magnetic particle imaging (MPI), which addresses these needs. We synthesize ∼200 nm magnetic nanoparticles and observe a macroscopic, collective effect in a homogeneous magnetic field with a rotating field vector. The nanoparticles form a millimeter-sized cloud and reach speeds of 8 mm s–1. This cloud is imaged and selectively steered with an MPI scanner. Our experimental results are supported by a model that highlights the role of the Mason number, the particle’s volume fraction, and the height of the cloud. The successful introduction of a fast swarm of microscopic units and the spatial selectivity of the technique suggest an effective approach to translate the use of micro- and nanobots into a clinical application.

Dates and versions

cea-03610678 , version 1 (16-03-2022)

Identifiers

Cite

Klaas Bente, Anna Bakenecker, Anselm von Gladiss, Felix Bachmann, Andrejs Ce̅bers, et al.. Selective Actuation and Tomographic Imaging of Swarming Magnetite Nanoparticles. ACS Applied Nano Materials, 2021, 4 (7), pp.6752-6759. ⟨10.1021/acsanm.1c00768⟩. ⟨cea-03610678⟩
14 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More