Additive-free selective methylation of secondary amines with formic acid over a Pd/In$_2$O$_3$ catalyst

Caroline Genre (1) , Idir Benaissa (1) , Timothé Godou (1) , Mathieu Pinault (2) , Thibault Cantat (1)

1 LCMCE - Laboratoire de Chimie Moléculaire et de Catalyse pour l'Energie (ex LCCEF)
2 LEDNA - Laboratoire Edifices Nanométriques

Formic acid is used as the sole carbon and hydrogen source in the methylation of aromatic and aliphatic amines to methylamines. The reaction proceeds via a formylation/transfer hydrogenation pathway over a solid Pd/In$_2$O$_3$ catalyst without the need for any additive.

Domains: Material chemistry; Catalysis

Caroline Genre, Idir Benaissa, Timothé Godou, Mathieu Pinault, Thibault Cantat. Additive-free selective methylation of secondary amines with formic acid over a Pd/In$_2$O$_3$ catalyst. Catalysis Science & Technology, In press, 12, pp.57-61. ⟨10.1039/D1CY01626A⟩. ⟨cea-03478547⟩