Abstract : During the last decade, time domain reflectometry (TDR) methods have formed the cornerstone for the diagnosis of transmission line networks. They have been adopted recently to the blind characterization of networks, thanks to graph theory and optimization based algorithms. Using a single testing point, it became possible to reconstruct the topology of a black-boxed network while returning precise estimates of branch lengths and most importantly load impedances. In other words, disconnecting the network for testing purposes is no longer needed. In this paper, we opted to perform a comparative analysis to study the effect of different optimisation based algorithms on the applicability of the aforementioned method. Particularly, we designed CAN bus networks based on real aeronautical cables of increased complexity to investigate their performance in terms of precision and computational burden.