Biogenesis and Functions of Exosomes and Extracellular Vesicles, Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools, vol.1448, pp.201-216, 2016. ,
Proteomic profiling of exosomes: Current perspectives, PROTEOMICS, vol.8, issue.19, pp.4083-4099, 2008. ,
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells, Nature Cell Biology, vol.9, issue.6, pp.654-659, 2007. ,
Multifaceted effects of oligodendroglial exosomes on neurons: impact on neuronal firing rate, signal transduction and gene regulation, Philosophical Transactions of the Royal Society B: Biological Sciences, vol.369, issue.1652, p.20130510, 2014. ,
Extracellular vesicles as mediators of neuron-glia communication, Frontiers in Cellular Neuroscience, vol.7, p.182, 2013. ,
Emerging Roles of Exosomes in Neuron?Glia Communication, Frontiers in Physiology, vol.3, p.119, 2012. ,
Neuronal Differentiation of Human Mesenchymal Stem Cells Using Exosomes Derived from Differentiating Neuronal Cells, PLOS ONE, vol.10, issue.8, p.e0135111, 2015. ,
Exosomes with Immune Modulatory Features Are Present in Human Breast Milk, The Journal of Immunology, vol.179, issue.3, pp.1969-1978, 2007. ,
Regulation of immune responses by extracellular vesicles, Nature Reviews Immunology, vol.14, issue.3, pp.195-208, 2014. ,
The Human Exosome and Disease, Advances in Experimental Medicine and Biology, vol.702, pp.132-142, 2010. ,
Exosomes-associated neurodegeneration and progression of Parkinson's disease, Am. J. Neurodegener. Dis, vol.1, pp.217-225, 2012. ,
The release and trans-synaptic transmission of Tau via exosomes, Molecular Neurodegeneration, vol.12, issue.1, p.5, 2017. ,
Exosomes and Homeostatic Synaptic Plasticity Are Linked to Each other and to Huntington's, Parkinson's, and Other Neurodegenerative Diseases by Database-Enabled Analyses of Comprehensively Curated Datasets, Frontiers in Neuroscience, vol.11, p.149, 2017. ,
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes, Nature Biotechnology, vol.29, issue.4, pp.341-345, 2011. ,
Tailored transgene expression to specific cell types in the central nervous system after peripheral injection with AAV9, Molecular Therapy - Methods & Clinical Development, vol.3, p.16081, 2016. ,
Enhancement of Adeno-Associated Virus Infection by Mobilizing Capsids into and Out of the Nucleolus, Journal of Virology, vol.83, issue.6, pp.2632-2644, 2008. ,
Epitope Mapping of Human Anti-Adeno-Associated Virus Type 2 Neutralizing Antibodies: Implications for Gene Therapy and Virus Structure, Journal of Virology, vol.74, issue.4, pp.1761-1766, 2000. ,
Naturally enveloped AAV vectors for shielding neutralizing antibodies and robust gene delivery in vivo, Biomaterials, vol.35, issue.26, pp.7598-7609, 2014. ,
Microvesicle-associated AAV Vector as a Novel Gene Delivery System, Molecular Therapy, vol.20, issue.5, pp.960-971, 2012. ,
Exosome-mediated transmission of hepatitis C virus between human hepatoma Huh7.5 cells, Proceedings of the National Academy of Sciences, vol.110, issue.32, pp.13109-13113, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02494666
Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV, Molecular Therapy, vol.25, issue.2, pp.379-391, 2017. ,
Exosome-associated AAV2 vector mediates robust gene delivery into the murine retina upon intravitreal injection, Scientific Reports, vol.7, issue.1, p.45329, 2017. ,
Fibered Confocal Fluorescence Microscopy (Cell-viZio?) Facilitates Extended Imaging in the Field of Microcirculation, Journal of Vascular Research, vol.41, issue.5, pp.400-411, 2004. ,
Hippocampal dysfunction in the pathophysiology of schizophrenia: a selective review and hypothesis for early detection and intervention, Molecular Psychiatry, vol.23, issue.8, pp.1764-1772, 2018. ,
Viral vectors and delivery strategies for CNS gene therapy, Therapeutic Delivery, vol.1, issue.4, pp.517-534, 2010. ,
Long-Term Clinical Improvement in MPTP-Lesioned Primates after Gene Therapy with AAV-hAADC, Molecular Therapy, vol.14, issue.4, pp.564-570, 2006. ,
Long-Term Clinical Improvement in MPTP-Lesioned Primates after Gene Therapy with AAV-hAADC, Molecular Therapy, vol.14, issue.4, pp.564-570, 2006. ,
Adeno-Associated Virus-Based Gene Therapy for CNS Diseases, Human Gene Therapy, vol.27, issue.7, pp.478-496, 2016. ,
Intracerebral Gene Therapy Using AAVrh.10-hARSA Recombinant Vector to Treat Patients with Early-Onset Forms of Metachromatic Leukodystrophy: Preclinical Feasibility and Safety Assessments in Nonhuman Primates, Human Gene Therapy Clinical Development, vol.26, issue.2, pp.113-124, 2015. ,
URL : https://hal.archives-ouvertes.fr/hal-01164426
Immune responses to AAV vectors: overcoming barriers to successful gene therapy, Blood, vol.122, issue.1, pp.23-36, 2013. ,
Viral and nonviral delivery systems for gene delivery, Advanced Biomedical Research, vol.1, issue.1, p.27, 2012. ,
Viral vectors for gene delivery to the central nervous system, Neurobiology of Disease, vol.48, issue.2, pp.179-188, 2012. ,
Lentiviral-Mediated Gene Transfer to the Sheep Brain: Implications for Gene Therapy in Batten Disease, Human Gene Therapy, vol.22, issue.8, pp.1011-1020, 2011. ,
Prevalence of Serum IgG and Neutralizing Factors Against Adeno-Associated Virus (AAV) Types 1, 2, 5, 6, 8, and 9 in the Healthy Population: Implications for Gene Therapy Using AAV Vectors, Human Gene Therapy, vol.21, issue.6, pp.704-712, 2010. ,
Overcoming Preexisting Humoral Immunity to AAV Using Capsid Decoys, Science Translational Medicine, vol.5, issue.194, pp.194ra92-194ra92, 2013. ,
URL : https://hal.archives-ouvertes.fr/hal-02881152
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vector, Brain Research, vol.713, issue.1-2, pp.99-107, 1996. ,
Neuron-Specific Transduction in the Rat Septohippocampal or Nigrostriatal Pathway by Recombinant Adeno-associated Virus Vectors, Experimental Neurology, vol.150, issue.2, pp.183-194, 1998. ,
Influence of promoter and WHV post-transcriptional regulatory element on AAV-mediated transgene expression in the rat brain, Gene Therapy, vol.7, issue.15, pp.1304-1311, 2000. ,
Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors, Human Gene Therapy, vol.22, issue.9, pp.1143-1153, 2011. ,
Factors affecting heterologous gene expression in Saccharomyces cerevisiae, Gene, vol.33, issue.2, pp.215-226, 1985. ,
Expression of the human interferon?? cDNA in yeast, Nucleic Acids Research, vol.11, issue.6, pp.1819-1837, 1983. ,
Efficient synthesis of enzymatically active calf chymosin in Saccharomyces cerevisiae, Gene, vol.24, issue.1, pp.1-14, 1983. ,
Regulated high efficiency expression of human interferon-alpha in Saccharomyces cerevisiae., The EMBO Journal, vol.1, issue.5, pp.603-608, 1982. ,
Recombinant adeno-associated virus type 2, 4, and 5 vectors: Transduction of variant cell types and regions in the mammalian central nervous system, Proceedings of the National Academy of Sciences, vol.97, issue.7, pp.3428-3432, 2000. ,
Analysis of Transduction Efficiency, Tropism and Axonal Transport of AAV Serotypes 1, 2, 5, 6, 8 and 9 in the Mouse Brain, PLoS ONE, vol.8, issue.9, p.e76310, 2013. ,
Intravenous Administration of Self-complementary AAV9 Enables Transgene Delivery to Adult Motor Neurons, Molecular Therapy, vol.17, issue.7, pp.1187-1196, 2009. ,
URL : https://hal.archives-ouvertes.fr/hal-02666576
Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes, Nature Biotechnology, vol.27, issue.1, pp.59-65, 2008. ,
Regional metabolic heterogeneity of the hippocampus is nonuniformly impacted by age and caloric restriction, Aging Cell, vol.15, issue.1, pp.100-110, 2015. ,
Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brain, Molecular Therapy, vol.13, issue.3, pp.528-537, 2006. ,
Expanded Repertoire of AAV Vector Serotypes Mediate Unique Patterns of Transduction in Mouse Brain, Molecular Therapy, vol.16, issue.10, pp.1710-1718, 2008. ,
Enhanced Survival of the LINCL Mouse Following CLN2 Gene Transfer Using the rh.10 Rhesus Macaque-derived Adeno-associated Virus Vector, Molecular Therapy, vol.15, issue.3, pp.481-491, 2007. ,
Gene transfer and expression in oligodendrocytes under the control of myelin basic protein transcriptional control region mediated by adeno-associated virus, Gene Therapy, vol.5, issue.1, pp.50-58, 1998. ,
Efficient Gene Delivery and Selective Transduction of Glial Cells in the Mammalian Brain by AAV Serotypes Isolated From Nonhuman Primates, Molecular Therapy, vol.17, issue.10, pp.1692-1702, 2009. ,
Intracellular transport of recombinant adeno-associated virus vectors, Gene Therapy, vol.19, issue.6, pp.649-658, 2012. ,
Infectious Entry Pathway of Adeno-Associated Virus and Adeno-Associated Virus Vectors, Journal of Virology, vol.74, issue.6, pp.2777-2785, 2000. ,
Adeno-associated virus vectors can be efficiently produced without helper virus, Gene Therapy, vol.5, issue.7, pp.938-945, 1998. ,
High AAV vector purity results in serotype- and tissue-independent enhancement of transduction efficiency, Gene Therapy, vol.17, issue.4, pp.503-510, 2009. ,
WITHDRAWN: Acknowledgements, The Rat Brain in Stereotaxic Coordinates, p.vii, 1982. ,