G. Rojas, J. M. Jimenez, and J. M. Gutierrez, Caprylic acid fractionation of hyperimmune horse plasma: Description of a simple procedure for antivenom production, Toxicon, vol.32, pp.351-363, 1994.

B. J. Hawgood, Doctor Albert Calmette 1863-1933: Founder of antivenomous serotherapy and of antituberculous BCG vaccination, Toxicon, vol.37, pp.1241-1258, 1999.

L. Wade, Drug industry. For Mexican antivenom maker, U.S. market is a snake pit, Science, vol.343, pp.16-17, 2014.

J. M. Gutierrez, G. Leon, and T. Burnouf, Antivenoms for the treatment of snakebite envenomings: The road ahead, Biol. J. Int. Assoc. Biol. Stand, vol.39, pp.129-142, 2011.

, WHO Guidelines for the Production, Control and Regulation of Snake Antivenom Immunoglobulins

J. W. Froude, B. Stiles, T. Pelat, and P. Thullier, Antibodies for biodefense, vol.3, pp.517-527, 2011.

B. Stechmann, S. K. Bai, E. Gobbo, R. Lopez, G. Merer et al., Inhibition of retrograde transport protects mice from lethal ricin challenge, Cell, vol.141, pp.231-242, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00509058

T. M. El-aziz, C. Ravelet, J. Molgo, E. Fiore, S. Pale et al., Efficient functional neutralization of lethal peptide toxins in vivo by oligonucleotides
URL : https://hal.archives-ouvertes.fr/hal-01639599

J. R. Hesselberth, D. Miller, J. Robertus, and A. D. Ellington, In vitro selection of RNA molecules that inhibit the activity of ricin A-chain, J. Biol. Chem, vol.275, pp.4937-4942, 2000.

R. J. Lewis, S. Dutertre, I. Vetter, and M. J. Christie, Conus venom peptide pharmacology, Pharmacol. Rev, vol.64, pp.259-298, 2012.
URL : https://hal.archives-ouvertes.fr/hal-02306916

E. C. Jimenez, B. M. Olivera, and R. W. Teichert, AlphaC-conotoxin PrXA. A new family of nicotinic acetylcholine receptor antagonists, Biochemistry, vol.46, pp.8717-8724, 2007.

M. R. Stratton, J. Darling, G. J. Pilkington, P. L. Lantos, B. R. Reeves et al., Characterization of the human cell line TE671, Carcinogenesis, vol.10, pp.899-905, 1989.

R. Schoepfer, M. Luther, and J. Lindstrom, The human medulloblastoma cell line TE671 expresses a muscle-like acetylcholine receptor. Cloning of the alpha-subunit cDNA, FEBS Lett, vol.226, pp.235-240, 1988.

Z. Shao, I. R. Mellor, M. J. Brierley, J. Harris, and P. N. Usherwood, Potentiation and inhibition of nicotinic acetylcholine receptors by spermine in the TE671 human muscle cell line, J. Pharmacol. Exp. Ther, vol.286, pp.1269-1276, 1998.

M. Zuker, Mfold web server for nucleic acid folding and hybridization prediction, Nucleic Acids Res, vol.31, pp.3406-3415, 2003.

S. C. Gopinath, K. Awazu, M. Fujimaki, K. Shimizu, W. Mizutani et al., Surface functionalization chemistries on highly sensitive silica-based sensor chips, Analyst, vol.137, pp.3520-3527, 2012.

, This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution, Sample Availability: Samples of the ?C-conotoxin PrXA are available from the authors. © 2019 by the authors. Licensee MDPI