Trimeric HIV Env provides epitope occlusion mediated by hypervariable loops

Carlos Moscoso , Li Xing , Jinwen Hui , Jeffrey Hu , Mohammad Baikoghli Kalkhoran , Onur Yenigun , Yide Sun (1) , Lassi Paavolainen , Loïc M Martin (2) , Anders Vahlne , Carlo Zambonelli , Susan Barnett , Indresh Srivastava (1) , R. Holland Cheng

1 Novartis Vaccines and Diagnostics [Siena]
2 DRF (CEA) - Direction de Recherche Fondamentale (CEA)

Domains: Chemical Sciences; Cristallography; Chemical Sciences; Medicinal Chemistry; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Biochemistry [q-bio.BM]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Structural Biology [q-bio.BM]; Life Sciences [q-bio]; Immunology; Immunotherapy

Carlos Moscoso, Li Xing, Jinwen Hui, Jeffrey Hu, Mohammad Baikoghli Kalkhoran, et al.. Trimeric HIV Env provides epitope occlusion mediated by hypervariable loops. Scientific Reports, 2015, 4 (1), ⟨10.1038/srep07025⟩. ⟨cea-02530807⟩