MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques

Nathalie Dereuddre-Bosquet (1) , Laurence Morellato-Castillo (2) , Joachim Brouwers , Patrick Augustijns (3) , Kawthar Bouchemal (4) , Gilles Ponchel (5) , Oscar Ramos , Carolina Herrera , Martha Stefanidou , Robin J Shattock (6) , Leo Heyndrickx , Guido Vanham (7) , Pascal Kessler (2) , Roger Le Grand (1) , Loïc M Martin (2)

1 IMVA - U1184 - Immunologie des Maladies Virales et Autoimmunes
2 DRF (CEA) - Direction de Recherche Fondamentale (CEA)
3 Lab Pharmacotechnology and Biopharmacy
4 IGPS - Institut Galien Paris-Sud
5 PCPB - Physico-chimie, pharmacotechnie, biopharmacie
6 Imperial College London
7 Department of Microbiology

Domaines: Chimie thérapeutique; Biochimie [q-bio.BM]; Immunothérapie; Médicaments

Nathalie Dereuddre-Bosquet, Laurence Morellato-Castillo, Joachim Brouwers, Patrick Augustijns, Kawthar Bouchemal, et al.. MiniCD4 Microbicide Prevents HIV Infection of Human Mucosal Explants and Vaginal Transmission of SHIV162P3 in Cynomolgus Macaques. PLoS Pathogens, 2012, 8 (12), pp.e1003071. ⟨10.1371/journal.ppat.1003071⟩. ⟨cea-02530573⟩