Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein

Antu Dey (1) , Brian Burke (2) , Yide Sun (1) , Klara Sirokman , Avishek Nandi , Karin Hartog , Ying Lian (1) , Anthony Geonnotti (3) , David C Montefiori (3) , Michael Franti , Grégoire Martin (4) , Andrea Carfi , Pascal Kessler (5) , Loïc M Martin (5) , Indresh Srivastava (1) , Susan Barnett

1 Novartis Vaccines and Diagnostics [Siena]
2 Appalachian State University
3 Duke University Medical Center
4 Centre de recherche du CEA/DSV/iBiTec-S/SIMOPRO
5 DRF (CEA) - Direction de Recherche Fondamentale (CEA)

Domains: Chemical Sciences; Medicinal Chemistry; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Biochemistry [q-bio.BM]; Life Sciences [q-bio]; Immunology; Vaccinology

Antu Dey, Brian Burke, Yide Sun, Klara Sirokman, Avishek Nandi, et al.. Elicitation of Neutralizing Antibodies Directed against CD4-Induced Epitope(s) Using a CD4 Mimetic Cross-Linked to a HIV-1 Envelope Glycoprotein. PLoS ONE, 2012, 7 (1), pp.e30233. ⟨10.1371/journal.pone.0030233⟩. ⟨cea-02530537⟩