Visible-Light-Driven Reduction of CO$_2$ to CO and Its Subsequent Valorization in Carbonylation Chemistry and $^{13}$C Isotope Labeling

Philipp Gotico (1) , Antonio Vecchio (2, 3) , Davide Audisio (4) , Annamaria Quaranta (1) , Zakaria Halime (5) , Winfried Leibl (1) , Ally Aukauloo (5, 1)

1 I2BC - Institut de Biologie Intégrative de la Cellule
2 SCBM - Service de Chimie Bio-Organique et de Marquage
3 IRAMAT - LMC - IRAMAT - Laboratoire Métallurgies et Cultures
4 LMC - Laboratoire de Marquage au Carbone 14
5 ICMMO - Institut de Chimie Moléculaire et des Matériaux d'Orsay

A convenient and safe approach in valorizing carbon monoxide (CO) produced from the photocatalytic reduction of carbon dioxide (CO$_2$) has been investigated. Visible light was used to drive an optimized photocatalytic reduction using a ruthenium trisbipyridine complex as a sensitizer and a rhenium bipyridyl carbonyl complex as a catalyst to perform an efficient reduction of CO2 to CO, which was then simultaneously utilized in a palladium-catalyzed aminocarbonylation reaction at room temperature. This approach provides a safe handling of the produced CO which also opens the way for a more efficient application of $^{13}$C-isotope and $^{14}$C-radioisotope labeled CO$_2$ in pharmaceutically-relevant drug labeling.

Keywords: artificial photosynthesis; carbon dioxide; carbonylation; isotopic labeling; photocatalysis

Domains: Organic chemistry; Catalysis

Philipp Gotico, Antonio Vecchio, Davide Audisio, Annamaria Quaranta, Zakaria Halime, et al.. Visible-Light-Driven Reduction of CO$_2$ to CO and Its Subsequent Valorization in Carbonylation Chemistry and $^{13}$C Isotope Labeling. ChemPhotoChem, 2018, 2 (8), pp.715-719. ⟨10.1002/cptc.201800012⟩. ⟨cea-02503934⟩