Versatile Access to N-Functionalized Iminosydnones by Carbonylimidazolium Activation

Margaux Riomet; Karine Porte; Léa Madegard; Pierre Thuéry; Davide Audisio; Frédéric Taran

Journal articles

Versatile Access to N-Functionalized Iminosydnones by Carbonylimidazolium Activation

Margaux Riomet ¹ Karine Porte ¹ Léa Madegard ¹ Pierre Thuéry ² Davide Audisio ³ Frédéric Taran ^{1, *}

* Corresponding author

1 SCBM - Service de Chimie Bio-Organique et de Marquage

2 LCMCE - Laboratoire de Chimie Moléculaire et de Catalyse pour l'Energie (ex LCCEF)

NIMBE UMR 3685 - Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M)

3 LMC - Laboratoire de Marquage au Carbone 14

SCBM - Service de Chimie Bio-Organique et de Marquage : DRF/JOLIOT

Abstract : A new methodology for N-exocyclic functionalization of iminosydnones was developed involving the addition of a large variety of nucleophiles on carbonyl-imidazolium activated iminosydnones. This practical and highly versatile method pro-vided access to new classes of iminosydnones and opened a straight-forward synthetic route to prepare iminosydnone-based prodrugs.

Document type :

Journal articles

Domain :

Chemical Sciences / Organic chemistry

Complete list of metadata

https://hal-cea.archives-ouvertes.fr/cea-02503416
Contributor : Davide Audisio Connect in order to contact the contributor
Submitted on : Monday, March 9, 2020 - 11:42:08 PM
Last modification on : Sunday, June 26, 2022 - 2:47:46 AM

Versatile Access to N-Functionalized Iminosydnones by Carbonylimidazolium Activation

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Versatile Access to N-Functionalized Iminosydnones by Carbonylimidazolium Activation

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