Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments

Damiano Fantini (1) , Eva Moritz , Frédéric Auvré (1) , Rachel Amouroux (2) , Anna Campalans (3) , Bernd Epe , Anne Bravard (1) , J. Pablo Radicella (4)

1 SCSR (U_967) - Stabilité génétique, Cellules Souches et Radiations
2 Centre de recherche du CEA/DSV/iBiTec-S/SIMOPRO
3 LRIG - Laboratoire de Recherche sur l'Instabilité Génétique
4 Institute of Cellular and Molecular Radiobiology

Domains: Subcellular Processes [q-bio.SC]; Biochemistry [q-bio.BM]

Damiano Fantini, Eva Moritz, Frédéric Auvré, Rachel Amouroux, Anna Campalans, et al.. Rapid inactivation and proteasome-mediated degradation of OGG1 contribute to the synergistic effect of hyperthermia on genotoxic treatments. DNA Repair, 2013, 12 (3), pp.227-237. ⟨10.1016/j.dnarep.2012.12.006⟩. ⟨cea-02386172⟩