Inductively-Coupled Microcoils and Solution Flow for Increased NMR Sensitivity

Guillaume Carret (1) , Thomas Berthelot (2) , Céline Boutin (1) , Patrick Berthault (1)

1 LSDRM - Laboratoire Structure et Dynamique par Résonance Magnétique (LCF)
2 LICSEN - Laboratoire Innovation en Chimie des Surfaces et NanoSciences

Inductively-Coupled Microcoils and Solution Flow for Increased NMR SensitivityGuillaume Carret, Thomas Berthelot, Céline Boutin, Patrick BerthaultNIMBE, CEA, CNRS, Paris-Saclay University, CEA Saclay, 91191 Gif-sur-Yvette, FranceTo circumvent the sensitivity problems inherent to slow return of magnetization to equilibrium in liquid-state NMR we present a 3D-printed NMR device based on a mini bubble-pump associated with fluidics and micro-detection that can be installed in every commercial liquid-state NMR probehead.It is based on the use of a closed-loop circuit ofthe solution near the NMR magnetic center, which presents two main advantages: i) pre-polarization is achieved for the whole solution volume, ii) this volume can be reduced to tens of microliters.

Domains: Material chemistry; Theoretical and/or physical chemistry

Guillaume Carret, Thomas Berthelot, Céline Boutin, Patrick Berthault. Inductively-Coupled Microcoils and Solution Flow for Increased NMR Sensitivity. 60th Experimental Nuclear Magnetic Resonance Conference, Apr 2019, Pacific Grove, United States. ⟨cea-02329455⟩