SO$_2$ conversion to sulfones: development and mechanistic insights of a sulfonylative Hiyama cross-coupling
Abstract
A sulfonylative Hiyama cross-coupling reaction using gaseous SO$_2$ is described, using Pd-catalysts. The use of silicon-based nucleophiles leads to the formation of allyl sulfones under mild conditions with a broad functional group tolerance. Control experiments coupled with DFT calculations shed light on the key steps of the reaction mechanism, revealing the crucial role of a transient sulfinate anion.
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