, p53 mediates cellular dysfunction and behavioral abnormalities in Huntington's disease, vol.47, pp.29-41, 2005.
Minocycline in phenotypic models of Huntington's disease, Neurobiol. Dis, vol.18, pp.206-217, 2005. ,
, Energetics in the pathogenesis of neurodegenerative diseases, vol.23, pp.298-304, 2000.
Involvement of mitochondrial complex II defects in neuronal death produced by N-terminus fragment of mutated huntingtin, Mol. Biol. Cell, vol.17, pp.1652-1663, 2006. ,
Calpain is a major cell death effector in selective striatal degeneration induced in vivo by 3-nitropropionate: implications for Huntington's disease, J. Neurosci, vol.23, pp.5020-5030, 2003. ,
Replicating Huntington's disease phenotype in experimental animals, Prog. Neurobiol, vol.59, pp.427-468, 1999. ,
3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease, J. Neurochem, vol.95, pp.1521-1540, 2005. ,
Microspheres containing insulin-like growth factor I for treatment of chronic neurodegeneration, Biomaterials, vol.25, pp.707-714, 2004. ,
Circulating insulinlike growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy, J. Neurosci, vol.21, pp.5678-5684, 2001. ,
Serum insulin-like growth factor I regulates brain amyloid-beta levels, Nat. Med, vol.8, pp.1390-1397, 2002. ,
Brain repair and neuroprotection by serum insulin-like growth factor I, Mol. Neurobiol, vol.27, pp.153-162, 2003. ,
Insulin growth factor-1 protects against excitotoxicity in the rat striatum, Neuroreport, vol.15, pp.2251-2254, 2004. ,
URL : https://hal.archives-ouvertes.fr/cea-02290615
Diabetes mellitus in Huntington disease, Clin. Genet, vol.27, pp.62-67, 1985. ,
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate, J. Neurochem, vol.64, pp.430-436, 1995. ,
Insulin-like growth factors I and II, Eur. J. Biochem, vol.190, pp.445-462, 1990. ,
The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt, Dev. Cell, vol.2, pp.831-837, 2002. ,
Neuronal death in Huntington's disease: multiple pathways for one issue, Neuronal Death by Accident or by Design, pp.137-152, 2001. ,
Mice transgenic for an expanded CAG repeat in the Huntington's disease gene develop diabetes Diabetes, vol.48, pp.649-651, 1999. ,
Brain mitochondrial defects amplify intracellular [Ca 2+ ] rise and neurodegeneration but not Ca 2+ entry during NMDA receptor activation, FASEB J, vol.20, pp.1021-1023, 2006. ,
URL : https://hal.archives-ouvertes.fr/hal-00103460
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model, Science, vol.301, pp.839-842, 2003. ,
Intranasal administration of insulin-like growth factor-I bypasses the blood-brain barrier and protects against focal cerebral ischemic damage, J. Neurol. Sci, vol.187, pp.91-97, 2001. ,
Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease, J. Neurosci, vol.18, pp.156-163, 1998. ,
Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration, J. Neurosci, vol.22, pp.4478-4486, 2002. ,
URL : https://hal.archives-ouvertes.fr/cea-02290628
Riluzole reduces incidence of abnormal movements but not striatal cell death in a primate model of progressive striatal degeneration, Exp. Neurol, vol.146, pp.135-141, 1997. ,
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines, Nat. Neurosci, vol.5, pp.731-736, 2002. ,
Central effects of the somatotropic system, Eur. J. Endocrinol, vol.149, pp.377-392, 2003. ,
, The Huntington study group, A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group, Cell, vol.72, pp.971-983, 1993.
Targeting energy metabolism in Huntington's disease, Lancet, vol.364, pp.312-313, 2004. ,
Molecular physiology, pathology, and regulation of the growth hormone/insulin-like growth factor-I system, Pediatr. Nephrol, vol.20, pp.295-302, 2005. ,