Clustering of Tau fibrils impairs the synaptic composition of α3‐Na + /K + ‐ ATP ase and AMPA receptors

Amulya Nidhi Shrivastava (1, 2) , Virginie Redeker (1, 2) , Laura Pieri (1, 2) , Luc Bousset (1, 2, 3) , Marianne Renner (4) , Karine Madiona (1, 2) , Caroline Mailhes‐hamon (3) , Audrey Coens (1, 2) , Luc Buée (5) , Philippe Hantraye (1, 2) , Antoine Triller (3) , Ronald Melki (1, 2)

1 LMN - Laboratoire des Maladies Neurodégénératives - UMR 9199
2 MIRCEN - Service MIRCEN
3 IBENS - Institut de biologie de l'ENS Paris
4 Institut du Fer à Moulin
5 JPArc - Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837

Keywords: cross‐talk of pathogenic proteins; misfolding disease; protein aggregation and clustering; single‐particle tracking; tauopathies

Domains: Life Sciences [q-bio]; Biochemistry, Molecular Biology; Life Sciences [q-bio]; Cellular Biology; Life Sciences [q-bio]; Neurons and Cognition [q-bio.NC]

Amulya Nidhi Shrivastava, Virginie Redeker, Laura Pieri, Luc Bousset, Marianne Renner, et al.. Clustering of Tau fibrils impairs the synaptic composition of α3‐Na + /K + ‐ ATP ase and AMPA receptors. EMBO Journal, 2019, 38 (3), pp.e99871. ⟨10.15252/embj.201899871⟩. ⟨cea-02279806⟩