The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation–suppressing activity

Di Wu (1, 2) , Jan Vonk (1) , Felix Salles (1) , Danara Vonk (1) , Martin Haslbeck (3) , Ronald Melki (4) , Steven Bergink (1) , Harm Kampinga (1)

1 Department of Biomedical Sciences of Cells and Systems, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
2 College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China
3 TUM - Technische Universität Munchen - Université Technique de Munich [Munich, Allemagne]
4 LMN - Laboratoire des Maladies Neurodégénératives - UMR 9199

Domains: Biochemistry, Molecular Biology; Cellular Biology

Di Wu, Jan Vonk, Felix Salles, Danara Vonk, Martin Haslbeck, et al.. The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation–suppressing activity. Journal of Biological Chemistry, 2019, 294 (25), pp.9985-9994. ⟨10.1074/jbc.RA118.007117⟩. ⟨cea-02279247⟩