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Evidence for a “metabolically inactive” inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T
Evidence for a “metabolically inactive” inorganic phosphate pool in adenosine triphosphate synthase reaction using localized 31P saturation transfer magnetic resonance spectroscopy in the rat brain at 11.7 T
Abstract : With the increased spectral resolution made possible at high fields, a second, smaller inorganic phosphate resonance can be resolved on $^{31}$P magnetic resonance spectra in the rat brain. Saturation transfer was used to estimate de $novo$ adenosine triphosphate synthesis reaction rate. While the main inorganic phosphate pool is used by adenosine triphos-phate synthase, the second pool is inactive for this reaction. Accounting for this new pool may not only help us understand $^{31}$P magnetic resonance spectroscopy metabolic profiles better but also better quantify adenosine triphos-phate synthesis.
Cited literature [26 references]
https://hal-cea.archives-ouvertes.fr/cea-02155315
Contributor : Julien Valette <>
Submitted on : Thursday, June 13, 2019 - 2:47:38 PM
Last modification on : Friday, July 3, 2020 - 11:52:03 AM
Contributor : Julien Valette <>
Submitted on : Thursday, June 13, 2019 - 2:47:38 PM
Last modification on : Friday, July 3, 2020 - 11:52:03 AM
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