I. Allaman, M. Belanger, and P. J. Magistretti, Astrocyteneuron metabolic relationships: for better and for worse, Trends Neurosci, vol.34, pp.76-87, 2011.

D. Attwell, A. M. Buchan, S. Charpak, M. Lauritzen, B. A. Macvicar et al., Glial and neuronal control of brain blood flow, Nature, vol.468, pp.232-243, 2010.

K. K. Ball, G. K. Gandhi, J. Thrash, N. F. Cruz, and G. A. Dienel, Astrocytic connexin distributions and rapid, extensive dye transfer via gap junctions in the inferior colliculus: implications for [(14)C]glucose metabolite trafficking, J. Neurosci. Res, vol.85, pp.3267-3283, 2007.

M. Belanger, I. Allaman, and P. J. Magistretti, Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation, Cell Metab, vol.14, pp.724-738, 2011.

M. V. Bennett, J. M. Garre, J. A. Orellana, F. F. Bukauskas, M. Nedergaard et al., Connexin and pannexin hemichannels in inflammatory responses of glia and neurons, Brain Res, vol.1487, pp.3-15, 2012.

Y. Bernardinelli, P. J. Magistretti, and J. Y. Chatton, Astrocytes generate Na+-mediated metabolic waves, Proc. Natl. Acad. Sci. U.S.A, vol.101, pp.14937-14942, 2004.

C. X. Bittner, R. Valdebenito, I. Ruminot, A. Loaiza, V. Larenas et al., Fast and reversible stimulation of astrocytic glycolysis by K+ and a delayed and persistent effect of glutamate, J. Neurosci, vol.31, pp.4709-4713, 2011.

A. M. Brown, H. M. Sickmann, K. Fosgerau, T. M. Lund, A. Schousboe et al., Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter, J. Neurosci. Res, vol.79, pp.74-80, 2005.

J. Y. Chatton, L. Pellerin, and P. J. Magistretti, GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission, Proc. Natl. Acad. Sci. U.S.A, vol.100, pp.12456-12461, 2003.

H. B. Choi, G. R. Gordon, N. Zhou, C. Tai, R. L. Rungta et al., Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase, Neuron, vol.75, pp.1094-1104, 2012.

M. L. Cotrina, J. Kang, J. H. Lin, E. Bueno, T. W. Hansen et al., Astrocytic gap junctions remain open during ischemic conditions, J. Neurosci, vol.18, pp.2520-2537, 1998.

M. L. Cotrina and M. Nedergaard, Brain connexins in demyelinating diseases: therapeutic potential of glial targets, Brain Res, vol.1487, pp.61-68, 2012.

D. A. Coulter and T. Eid, Astrocytic regulation of glutamate homeostasis in epilepsy, Glia, vol.60, pp.1215-1226, 2012.

M. Cronin, P. N. Anderson, J. E. Cook, C. R. Green, and D. L. Becker, Blocking connexin43 expression reduces inflammation and improves functional recovery after spinal cord injury, Mol. Cell Neurosci, vol.39, pp.152-160, 2008.

D. Pina-benabou, M. H. Srinivas, M. Spray, D. C. Scemes, and E. , Calmodulin kinase pathway mediates the K+-induced increase in Gap junctional communication between mouse spinal cord astrocytes, J. Neurosci, vol.21, pp.6635-6643, 2001.

M. O. Enkvist and K. D. Mccarthy, Astroglial gap junction communication is increased by treatment with either glutamate or high K+ concentration, 1994.

, J. Neurochem, vol.62, pp.489-495

C. Escartin, E. Brouillet, P. Gubellini, Y. Trioulier, C. Jacquard et al., Ciliary neurotrophic factor activates astrocytes, redistributes their glutamate transporters GLAST and GLT-1 to raft microdomains, and improves glutamate handling in vivo, J. Neurosci, vol.26, pp.5978-5989, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00088896

C. Escartin, K. Pierre, A. Colin, E. Brouillet, T. Delzescaux et al., Activation of astrocytes by CNTF induces metabolic plasticity and increases resistance to metabolic insults, J. Neurosci, vol.27, pp.7094-7104, 2007.

E. A. Eugenin and J. W. Berman, Gap junctions mediate human immunodeficiency virusbystander killing in astrocytes, J. Neurosci, vol.27, pp.12844-12850, 2007.

E. A. Eugenin, J. E. Clements, M. C. Zink, and J. W. Berman, junctiondependent mechanism, J. Neurosci, vol.31, pp.9456-9465, 2011.

R. Farahani, M. H. Pina-benabou, A. Kyrozis, A. Siddiq, P. C. Barradas et al., Alterations in metabolism and gap junction expression may determine the role of astrocytes as "good samaritans" or executioners, Glia, vol.50, pp.351-361, 2005.

G. Fischer and H. Kettenmann, Cultured astrocytes form a syncytium after maturation, Exp. Cell Res, vol.159, pp.273-279, 1985.

M. V. Frantseva, L. Kokarovtseva, C. G. Naus, P. L. Carlen, D. Macfabe et al., Specific gap junctions enhance the neuronal vulnerability to brain traumatic injury, J. Neurosci, vol.22, pp.644-653, 2002.

M. V. Frantseva, L. Kokarovtseva, P. Velazquez, and J. L. , Ischemia-induced brain damage depends on specific gap-junctional coupling, J. Cereb. Blood Flow Metab, vol.22, pp.453-462, 2002.

C. Giaume, A. Koulakoff, L. Roux, D. Holcman, and N. Rouach, Astroglial networks: a step further in neuroglial and gliovascular interactions, Nat. Rev. Neurosci, vol.11, pp.87-99, 2010.

M. Guzman and C. Blazquez, Is there an astrocyte-neuron ketone body shuttle?, Trends Endocrinol. Metab, vol.12, pp.169-173, 2001.

J. J. Harris, R. Jolivet, A. , and D. , Synaptic energy use and supply, Neuron, vol.75, pp.762-777, 2012.

V. Houades, A. Koulakoff, P. Ezan, I. Seif, and C. Giaume, Gap junction-mediated astrocytic networks in the mouse barrel cortex, J. Neurosci, vol.28, pp.5207-5217, 2008.

V. Houades, N. Rouach, P. Ezan, F. Kirchhoff, A. Koulakoff et al., Shapes of astrocyte networks in the juvenile brain, Neuron Glia Biol, vol.2, pp.3-14, 2006.

F. Hyder, A. B. Patel, A. Gjedde, D. L. Rothman, K. L. Behar et al., Neuronal-glial glucose oxidation and glutamatergic-GABAergic function, J. Cereb. Blood Flow Metab, vol.26, pp.865-877, 2006.

T. Kielian and N. Esen, Effects of neuroinflammation on glia-glia gap junctional intercellular communication: a perspective, Neurochem. Int, vol.45, pp.429-436, 2004.

A. Koulakoff, X. Mei, J. A. Orellana, J. C. Saez, and C. Giaume, , 2012.

, Glial connexin expression and function in the context of Alzheimer's disease, Biochim. Biophys. Acta, vol.1818, pp.2048-2057

K. V. Kuchibhotla, C. R. Lattarulo, B. T. Hyman, and B. J. Bacskai, Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice, Science, vol.323, pp.1211-1215, 2009.

N. Kuga, T. Sasaki, Y. Takahara, N. Matsuki, and Y. Ikegaya, , 2011.

, Large-scale calcium waves traveling through astrocytic networks in vivo, J. Neurosci, vol.31, pp.2607-2614

J. Langer, J. Stephan, M. Theis, and C. R. Rose, Gap junctions mediate intercellular spread of sodium between hippocampal astrocytes in situ, Glia, vol.60, pp.239-252, 2012.

J. H. Lin, H. Weigel, M. L. Cotrina, S. Liu, E. Bueno et al., Gap-junctionmediated propagation and amplification of cell injury, Nat. Neurosci, vol.1, pp.494-500, 1998.

M. T. Lin and M. F. Beal, Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases, Nature, vol.443, pp.787-795, 2006.

M. Maalouf, J. M. Rho, and M. P. Mattson, The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies, Brain Res. Rev, vol.59, pp.293-315, 2009.

P. J. Magistretti, O. Sorg, and J. L. Martin, Regulation of glycogen metabolism in astrocytes: physiological, pharmacological, and pathological aspects, pp.243-265, 1993.

H. Marrero and R. K. Orkand, Nerve impulses increase glial intercellular permeability, Glia, vol.16, pp.285-289, 1996.

V. Matyash and H. Kettenmann, Heterogeneity in astrocyte morphology and physiology, Brain Res. Rev, vol.63, pp.2-10, 2010.

M. C. Mckenna, The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain, J. Neurosci. Res, vol.85, pp.3347-3358, 2007.

W. Meme, C. F. Calvo, N. Froger, P. Ezan, E. Amigou et al., Proinflammatory cytokines released from microglia inhibit gap junctions in astrocytes: potentiation by beta-amyloid, 2006.

, FASEB J, vol.20, pp.494-496

J. I. Nagy, D. Patel, P. A. Ochalski, and G. L. Stelmack, Connexin30 in rodent, cat and human brain: selective expression in gray matter astrocytes, co-localization with connexin43 at gap junctions and late developmental appearance, Neuroscience, vol.88, pp.447-468, 1999.

T. Nakase, S. Fushiki, G. Sohl, M. Theis, K. Willecke et al., Neuroprotective role of astrocytic gap junctions in ischemic stroke, Cell Commun. Adhes, vol.10, pp.413-417, 2003.

M. Nedergaard and A. Verkhratsky, Artifact versus reality-how astrocytes contribute to synaptic events, Glia, vol.60, pp.1013-1023, 2012.

J. A. Orellana, R. Von-bernhardi, C. Giaume, and J. C. Saez, , 2012.

, Glial hemichannels and their involvement in aging and neurodegenerative diseases, Rev. Neurosci, vol.23, pp.163-177

L. Pellerin, A. K. Bouzier-sore, A. Aubert, S. Serres, M. Merle et al., Activity-dependent regulation of energy metabolism by astrocytes: an update, Glia, vol.55, pp.1251-1262, 2007.

L. Pellerin and P. J. Magistretti, Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization, Proc. Natl. Acad. Sci. U.S.A, vol.91, pp.10625-10629, 1994.

O. Peters, C. G. Schipke, A. Philipps, B. Haas, U. Pannasch et al., Astrocyte function is modified by Alzheimer's disease-like pathology in aged mice, J. Alzheimers Dis, vol.18, pp.177-189, 2009.

M. L. Prins, Cerebral ketone metabolism during development and injury, Epilepsy Res, vol.100, pp.218-223, 2012.

N. Rouach, E. Avignone, W. Meme, A. Koulakoff, L. Venance et al., Gap junctions and connexin expression in the normal and pathological central nervous system, Biol. Cell, vol.94, pp.457-475, 2002.
URL : https://hal.archives-ouvertes.fr/hal-02149139

N. Rouach, M. Tence, J. Glowinski, and C. Giaume, Costimulation of N-methyl-Daspartate and muscarinic neuronal receptors modulates gap junctional communication in striatal astrocytes, Proc. Natl. Acad. Sci. U.S.A, vol.99, pp.1023-1028, 2002.

N. Rouach, J. Glowinski, and C. Giaume, Activitydependent neuronal control of gapjunctional communication in astrocytes, J. Cell Biol, vol.149, pp.1513-1526, 2000.

N. Rouach, A. Koulakoff, V. Abudara, K. Willecke, and C. Giaume, Astroglial metabolic networks sustain hippocampal synaptic transmission, Science, vol.322, pp.1551-1555, 2008.

N. Rouach, M. Segal, A. Koulakoff, C. Giaume, A. et al., Carbenoxolone blockade of neuronal network activity in culture is not mediated by an action on gap junctions, J. Physiol, vol.553, pp.729-745, 2003.

L. Roux, K. Benchenane, J. D. Rothstein, G. Bonvento, and C. Giaume, Plasticity of astroglial networks in olfactory glomeruli, Proc. Natl. Acad. Sci. U.S.A, vol.108, pp.18442-18446, 2011.

I. Ruminot, R. Gutierrez, G. Penamunzenmayer, C. Anazco, T. Sotelo-hitschfeld et al., NBCe1 mediates the acute stimulation of astrocytic glycolysis by extracellular K+, J. Neurosci, vol.31, pp.14264-14271, 2011.

M. Simard, G. Arcuino, T. Takano, Q. S. Liu, and M. Nedergaard, Signaling at the gliovascular interface, J. Neurosci, vol.23, pp.9254-9262, 2003.

C. Steinhauser, G. Seifert, and P. Bedner, Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling, Glia, vol.60, pp.1192-1202, 2012.

A. Suzuki, S. A. Stern, O. Bozdagi, G. W. Huntley, R. H. Walker et al., , 2011.

, Astrocyte-neuron lactate transport is required for long-term memory formation, Cell, vol.144, pp.810-823

M. Theis and C. Giaume, Connexin-based intercellular communication and astrocyte heterogeneity, Brain Res, vol.1487, pp.88-98, 2012.

J. P. Vessey, M. R. Lalonde, H. A. Mizan, N. C. Welch, M. E. Kelly et al., Carbenoxolone inhibition of voltage-gated Ca channels and synaptic transmission in the retina, J. Neurophysiol, vol.92, pp.1252-1256, 2004.