Feedback control of microbubble cavitation for ultrasound-mediated blood–brain barrier disruption in non-human primates under magnetic resonance guidance

Hermes Kamimura (1, 2) , Julien Flament (1, 3, 4) , Julien Valette (1, 4) , Andrea Cafarelli (2, 5) , Romina Aron Badin (4, 1) , Philippe Hantraye (4, 1) , Benoit Larrat (2)

1 MIRCEN - Service MIRCEN
2 NEUROSPIN - Service NEUROSPIN
3 INSERM - Institut National de la Santé et de la Recherche Médicale
4 LMN - Laboratoire des Maladies Neurodégénératives - UMR 9199
5 The BioRobotics Institute

Keywords: Blood–brain barrier; magnetic resonance imaging; primate; interventional neuroradiology; ultrasound

Domains: Life Sciences [q-bio]; Bioengineering; Imaging; Physics [physics]; Mechanics [physics]; Acoustics [physics.class-ph]

Hermes Kamimura, Julien Flament, Julien Valette, Andrea Cafarelli, Romina Aron Badin, et al.. Feedback control of microbubble cavitation for ultrasound-mediated blood–brain barrier disruption in non-human primates under magnetic resonance guidance. Journal of Cerebral Blood Flow and Metabolism, 2018, pp.753514. ⟨10.1177/0271678x17753514⟩. ⟨cea-02043269⟩