Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic

Grégoire Martin (1) , Brian Burke (2) , Robert Thai (3) , Antu Dey (2) , Olivier Combes (3) , Bernadette Heyd (1) , Anthony Geonnotti (4) , David C Montefiori (4) , Elaine Kan (2) , Ying Lian (2) , Yide Sun (2) , Toufik Abache (1) , Jeffrey Ulmer (2) , Hocine Madaoui (5) , Raphaël Guérois (6) , Susan W Barnett (7) , Indresh Srivastava (2) , Pascal Kessler (3) , Loïc M Martin (3)

1 Centre de recherche du CEA/DSV/iBiTec-S/SIMOPRO
2 Novartis Vaccines and Diagnostics [Siena]
3 SIMoS - Service d'Ingénierie Moléculaire pour la Santé (ex SIMOPRO)
4 Duke University Medical Center
5 IBITECS - Institut de Biologie et de Technologies de Saclay
6 AMIG - Assemblage moléculaire et intégrité du génome
7 Novartis Vaccines

Domains: Chemical Sciences; Analytical chemistry; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Structural Biology [q-bio.BM]; Life Sciences [q-bio]; Biotechnology; Life Sciences [q-bio]; Pharmaceutical sciences; Medication; Life Sciences [q-bio]; Human health and pathology; Infectious diseases; Life Sciences [q-bio]; Immunology; Vaccinology

Grégoire Martin, Brian Burke, Robert Thai, Antu Dey, Olivier Combes, et al.. Stabilization of HIV-1 Envelope in the CD4-bound Conformation through Specific Cross-linking of a CD4 Mimetic. Journal of Biological Chemistry, 2011, 286 (24), pp.21706-21716. ⟨cea-01989703⟩