Comparative methylome analysis of ICF patients identifies heterochromatin loci that require ZBTB24, CDCA7 and HELLS for their methylated state

Guillaume Velasco (1) , Giacomo Grillo , Nizar Touleimat (2) , Laure Ferry (3) , Ivana Ivkovic (4) , Florence Ribierre (5) , Jean-François Deleuze (6) , Sophie Chantalat (5) , Capucine Picard (7) , Claire Francastel (1)

1 EDC - Centre épigénétique et destin cellulaire
2 IBISC - Informatique, Biologie Intégrative et Systèmes Complexes
3 EDC - Centre épigénétique et destin cellulaire
4 Institut de la Vision
5 CNG - Centre National de Génotypage
6 Sanofi-Aventis
7 Inserm U980 - Génétique Humaine des Maladies Infectieuses

Domains: Statistics [stat]; Machine Learning [stat.ML]; Life Sciences [q-bio]; Biochemistry, Molecular Biology; Cellular Biology; Quantitative Methods [q-bio.QM]; Cancer; Genetics; Human genetics; Human health and pathology

Guillaume Velasco, Giacomo Grillo, Nizar Touleimat, Laure Ferry, Ivana Ivkovic, et al.. Comparative methylome analysis of ICF patients identifies heterochromatin loci that require ZBTB24, CDCA7 and HELLS for their methylated state. Human Molecular Genetics, 2018, 27 (14), pp.2409 - 2424. ⟨10.1093/hmg/ddy130⟩. ⟨cea-01833124⟩