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Azo-polysiloxanes as new supports for cell cultures

Nicolae Hurduc 1, * Alina Macovei 2 Cristina Paius 1 Alina Raicu 1 Ioana Moleavin 3 Norica Branza-Nichita 2, * Matthieu Hamel 3 Licinio Rocha 3, *
* Corresponding author
1 "Ghorghe Asachi" Technical University of Iasi, Faculty of Chemical Engineering
2 Institute of Biochemistry of the Romanian Academy
3 LCAE - Laboratoire Capteurs et Architectures Electroniques
DM2I - Département Métrologie Instrumentation & Information : DRT/LIST/DM2I
Abstract : The paper introduces a new class of materials with azo-polysiloxanic structure bearing the property to generate nano-structured surfaces by laser irradiation. The ability to modulate the optical response of the film, through a modification of the polymer chemical structure, has been investigated. The azo-materials were tested for their ability to support cell adhesion and growth, with very promising results. A future use of these materials as growth support in cell cultures is of great interest, due to an easy, one step-method to generate the surface relief grating and to the possibility to introduce a large range of chemical modifications due to the presence of the chlorobenzyl groups in the polymeric side-chain.
Keywords : Azo-polysiloxanes Cell cultures Laser nano-structuration Surface relief gratings
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https://hal-cea.archives-ouvertes.fr/cea-01802293
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Submitted on : Tuesday, May 29, 2018 - 10:59:05 AM
Last modification on : Friday, June 25, 2021 - 10:00:02 AM

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Nicolae Hurduc, Alina Macovei, Cristina Paius, Alina Raicu, Ioana Moleavin, et al.. Azo-polysiloxanes as new supports for cell cultures. Materials Science and Engineering: C, Elsevier, 2013, 33 (4), pp.2440 - 2445. ⟨10.1016/j.msec.2013.01.012⟩. ⟨cea-01802293⟩

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