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Synthesis of a multi-branched porphyrin-oligonucleotide scaffold for the construction of DNA-Based nano-architecture

Grégory Chatelain 1 Guillaume Clavé 1 Didier Gasparutto 2 Eric Le Cam 3 Olivier Piétrement 3 Stéphane Campidelli 1 
1 LICSEN - Laboratoire Innovation en Chimie des Surfaces et NanoSciences
NIMBE UMR 3685 - Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M)
2 LAN - Laboratoire Lésions des Acides Nucléiques
SCIB - UMR E3 - Service de Chimie Inorganique et Biologique : DSM/INAC/SCIB
3 UMR8126 - Signalisation, noyaux et innovations en cancérologie
Abstract : Porphytin-oligonudeotide hybrids containing one to four DNA strands (P1-P4) have been synthesised and fully characterised. The hybrid P4, which inserts one porphyrin and four DNA fragments, was combined with gold nanoparticles and images by electron microscopy.
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https://hal-cea.archives-ouvertes.fr/cea-01709773
Contributor : Serge Palacin Connect in order to contact the contributor
Submitted on : Thursday, February 15, 2018 - 11:41:00 AM
Last modification on : Saturday, June 25, 2022 - 10:29:35 PM

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CEA | UGA | CNRS | FNCLCC | IGR | INAC-SCIB | PUBNIMBE | INC-CNRS | IRAMIS-NIMBE | CEA-UPSAY | UNIV-PARIS-SACLAY | LRN | CEA-DRF | IRIG | CEA-GRE | ANR | GS-ENGINEERING | IRAMIS | GS-CHIMIE | INSTITUT-SCIENCES-LUMIERE

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Grégory Chatelain, Guillaume Clavé, Didier Gasparutto, Eric Le Cam, Olivier Piétrement, et al.. Synthesis of a multi-branched porphyrin-oligonucleotide scaffold for the construction of DNA-Based nano-architecture. Collection of Czechoslovak Chemical Communications, Institute of Organic Chemistry & Biochemistry, 2015, ⟨10.1135/css201414197⟩. ⟨cea-01709773⟩

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