Solid-State $^{17}$O NMR Studies of Biomolecules

Alan Wong 1 Fabrizio Poli 1
1 LSDRM - Laboratoire Structure et Dynamique par Résonance Magnétique (LCF)
NIMBE UMR 3685 - Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M)
Abstract : Since the 1990s, we have witnessed a steady progress in solid-state $^{17}$O NMR spectroscopy for biomolecules. Up until today, majority of the reported studies are considered as preliminary works, but significant, for laying the foundations of $^{17}$O NMR applications to biological solids. This has taken over 20 years with nearly 100 studies in methodology developments and NMR assessments. Currently, the field is entering an exciting stage where small biomolecules can routinely be characterized and new area of research can be exploited, such as investigations of macromolecules and multi-dimensional correlation experiments. This review provides a summary of the important contributions and millstones in the field, including the methodologies for probing the dilute $^{17}$O-spin in biomolecules and the investigations of the nuclear properties in relationships to the oxygen local surroundings.
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Soumis le : mercredi 15 novembre 2017 - 12:23:22
Dernière modification le : vendredi 16 mars 2018 - 01:14:19

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Alan Wong, Fabrizio Poli. Solid-State $^{17}$O NMR Studies of Biomolecules. Annual Reports on NMR Spectroscopy, Elsevier, 2014, 83, pp.145-220. 〈http://www.sciencedirect.com/science/article/pii/B9780128001837000034?via%3Dihub〉. 〈10.1016/b978-0-12-800183-7.00003-4〉. 〈cea-01635550〉

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