Elucidating Dramatic Ligand Effects on SET Processes: Iron Hydride versus Iron Borohydride Catalyzed Reductive Radical Cyclization of Unsaturated Organic Halides
Université Paris-Saclay (Espace Technologique, Bat. Discovery - RD 128 - 2e ét., 91190 Saint-Aubin - France)
Abstract : An iron(II) borohydride complex ([(η1-H3BH)FeCl(NCCH3)4]) is employed as the precatalyst in iron-catalyzed radical cyclizations of unsaturated organic halides in the presence of NaBH4. Mechanistic investigations have established that the ligand bound to the metal center (acetonitrile versus ethylenebis(diphenylphosphine) (dppe)) plays a crucial role in the structure and reactivity of the active anionic iron(I) hydride ([HFeCl(dppe)2]−) and borohydride ([(η1-H3BH)FeCl(NCCH3)4]−) with unsaturated haloacetals. This work provides new insights into iron(I) hydride and borohydride species and their potential implication in single-electron processes.
https://hal-cea.archives-ouvertes.fr/cea-01608951
Contributeur : Serge Palacin
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Soumis le : mardi 3 octobre 2017 - 07:08:46
Dernière modification le : samedi 21 avril 2018 - 12:38:02
Sara Kyne, Martin Clémancey, Geneviève Blondin, Etienne Derat, Louis Fensterbank, et al.. Elucidating Dramatic Ligand Effects on SET Processes: Iron Hydride versus Iron Borohydride Catalyzed Reductive Radical Cyclization of Unsaturated Organic Halides. Organometallics, American Chemical Society, 2017, 37, pp.761-771. 〈http://dx.doi.org/10.1021/acs.organomet.7b00603〉. 〈10.1021/acs.organomet.7b00603〉. 〈cea-01608951〉
