Xe NMR-based sensors: biological applications and recent methods - CEA - Commissariat à l’énergie atomique et aux énergies alternatives Accéder directement au contenu
Article Dans Une Revue Analyst Année : 2017

Xe NMR-based sensors: biological applications and recent methods

Résumé

Xenon is a first-rate sensor of biological events, due to its large polarizable electron cloud inducing significant modification of NMR parameters through slight changes in its local environment. The use of xenon as a sensor is of increasing interest for sensitive magnetic resonance imaging, since its signal can be enhanced by several orders of magnitude, mainly by spin-exchange optical pumping. Furthermore xenon can be vectorized toward targets of interest by using functionalized host systems, enabling their detection at subnanomolar concentrations. Associated with a new generation of detection methods this gives rise to a powerful molecular imaging approach, where xenon can be delivered on purpose several times after introduction of the functionalized host system.

Domaines

Matériaux
Fichier principal
Vignette du fichier
C7an01088e_V0.pdf (2.39 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)
Loading...

Dates et versions

cea-01573931 , version 1 (11-08-2017)

Licence

Paternité

Identifiants

Citer

E Mari, P Berthault. Xe NMR-based sensors: biological applications and recent methods. Analyst, 2017, 142, pp.3298-3308. ⟨10.1039/C7AN01088E⟩. ⟨cea-01573931⟩
72 Consultations
370 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More