Skip to Main content Skip to Navigation
Journal articles

Xe NMR-based sensors: biological applications and recent methods

E Mari 1 P Berthault 1 
1 LSDRM - Laboratoire Structure et Dynamique par Résonance Magnétique (LCF)
NIMBE UMR 3685 - Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M)
Abstract : Xenon is a first-rate sensor of biological events, due to its large polarizable electron cloud inducing significant modification of NMR parameters through slight changes in its local environment. The use of xenon as a sensor is of increasing interest for sensitive magnetic resonance imaging, since its signal can be enhanced by several orders of magnitude, mainly by spin-exchange optical pumping. Furthermore xenon can be vectorized toward targets of interest by using functionalized host systems, enabling their detection at subnanomolar concentrations. Associated with a new generation of detection methods this gives rise to a powerful molecular imaging approach, where xenon can be delivered on purpose several times after introduction of the functionalized host system.
Document type :
Journal articles
Complete list of metadata

Cited literature [52 references]  Display  Hide  Download
Contributor : Serge Palacin Connect in order to contact the contributor
Submitted on : Friday, August 11, 2017 - 8:56:36 AM
Last modification on : Friday, January 7, 2022 - 3:54:08 AM


Files produced by the author(s)


Distributed under a Creative Commons Attribution 4.0 International License



E Mari, P Berthault. Xe NMR-based sensors: biological applications and recent methods. Analyst, Royal Society of Chemistry, 2017, 142, pp.3298-3308. ⟨10.1039/C7AN01088E⟩. ⟨cea-01573931⟩



Record views


Files downloads