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Method for obtaining three-dimensional actin structures and uses thereof

Abstract : The present invention relates to a method for preparing three-dimensional actin structures having a well-defined shape and displaying improved mechanical rigidity. This method comprises the steps of (a) providing a polymerization solution comprising actin monomers, a branching agent and a capping agent, (b) providing at least one surface having thereon a pattern which is coated with a nucleating agent, and (c) contacting the at least one surface of step (b) with the polymerization solution of step (a) so as to induce the polymerization of actin and obtain the said desired three-dimensional actin structure. Applications of the present invention in various technological fields such as microelectronics are also provided
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https://hal-cea.archives-ouvertes.fr/cea-01550186
Contributor : Jean Christophe Gabriel <>
Submitted on : Thursday, June 29, 2017 - 2:05:10 PM
Last modification on : Tuesday, September 22, 2020 - 2:46:02 PM

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  • HAL Id : cea-01550186, version 1

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Jean Christophe Gabriel, Laurent Blanchoin, Manuel Thery, Remi Galland. Method for obtaining three-dimensional actin structures and uses thereof. United States, Patent n° : 9070702. 2015. ⟨cea-01550186⟩

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