Abstract : In this Article we show that circulation of the sample in a closed-loop circuit combined to micro sized detection can lead to a significant signal NMR enhancement. We present an optimized NMR device based on a mini bubble-pump associated to fluidics and microdetection that can be installed on a commercial NMR spectrometer. In addition to a significant signal enhancement for slowly relaxing nuclei, we show that it enables more precise and frequent monitoring of chemical reactions. An additional modification leads to a stopped-flow system very efficient for instance for 2D NMR experiments with long mixing times.
https://hal-cea.archives-ouvertes.fr/cea-01449824
Contributeur : Serge Palacin
<>
Soumis le : lundi 30 janvier 2017 - 17:19:03
Dernière modification le : jeudi 15 mars 2018 - 15:07:00
