Nonlinear detection of secondary isotopic chemical shifts in NMR through spin noise

* Corresponding author
2 LSDRM - Laboratoire Structure et Dynamique par Résonance Magnétique (LCF)
NIMBE UMR 3685 - Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M)
Abstract : The detection of minor species in the presence of large amounts of similar main components remains a key challenge in analytical chemistry, for instance, to obtain isotopic fingerprints. As an alternative to the classical NMR scheme based on coherent excitation and detection, here we introduce an approach based on spin-noise detection. Chemical shifts and transverse relaxation rates are determined using only the detection circuit. Thanks to a nonlinear effect in mixtures with small chemical shift dispersion, small signals on top of a larger one can be observed with increased sensitivity as bumps on a dip; the latter being the signature of the main magnetization. Experimental observations are underpinned by an analytical theory: the coupling between the magnetization and the coil provides an amplified detection capability of both small static magnetic field inhomogeneities and small NMR signals. This is illustrated by two-bond $^{12}$C/ $^{13}$C isotopic measurements.
Document type :
Journal articles
Domain :

Cited literature [31 references]

https://hal-cea.archives-ouvertes.fr/cea-01430332
Contributor : Serge Palacin <>
Submitted on : Monday, January 9, 2017 - 5:05:50 PM
Last modification on : Thursday, May 23, 2019 - 2:44:14 PM
Long-term archiving on: Monday, April 10, 2017 - 4:06:02 PM

File

ncomms13914.pdf
Publisher files allowed on an open archive

Citation

Maria Pöschko, Victor Rodin, Judith Schlagnitweit, Norbert Müller, Hervé Desvaux. Nonlinear detection of secondary isotopic chemical shifts in NMR through spin noise. Nature Communications, Nature Publishing Group, 2017, 8, pp.13914. ⟨10.1038/ncomms13914⟩. ⟨cea-01430332⟩

Record views