Permeation through Lipid Bilayers by Adhesion of Giant Vesicles on Decorated Surfaces

Anne-Laure Bernard (1) , Marie-Alice Guedeau-Boudeville (1) , Olivier Sandre (2) , Serge Palacin (3) , Jean-Marc Di Meglio (4) , Ludovic Jullien (5)

1 LPMC - Laboratoire de Physique de la Matière Condensée
2 PCC - Physico-Chimie-Curie
3 SCM - Service de Chimie Moléculaire
4 ICS - Institut Charles Sadron
5 Département de Chimie - ENS Paris

We describe the dynamics of interaction of giant vesicles with properly designed decorated surfaces. The spreading of the vesicles leads to major deformations and is accompanied by the creation of transient macroscopic pores in the micrometer range. Different phenomena that have been observed by changing either the characteristic scale or the geometry of the decorated surfaces are reported and discussed.

Domains: Chemical Sciences; Material chemistry; Physics [physics]; Condensed Matter [cond-mat]; Soft Condensed Matter [cond-mat.soft]

Anne-Laure Bernard, Marie-Alice Guedeau-Boudeville, Olivier Sandre, Serge Palacin, Jean-Marc Di Meglio, et al.. Permeation through Lipid Bilayers by Adhesion of Giant Vesicles on Decorated Surfaces. Langmuir, 2000, 16, pp.6801-6808. ⟨10.1021/la991342p⟩. ⟨cea-01056990⟩