Estimation of the hemodynamic response in event-related functional MRI: Bayesian networks as a framework for efficient Bayesian modeling and inference. - Archive ouverte HAL Access content directly
Journal Articles IEEE Transactions on Medical Imaging Year : 2004

Estimation of the hemodynamic response in event-related functional MRI: Bayesian networks as a framework for efficient Bayesian modeling and inference.

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Abstract

A convenient way to analyze blood-oxygen-level-dependent functional magnetic resonance imaging data consists of modeling the whole brain as a stationary, linear system characterized by its transfer function: the hemodynamic response function (HRF). HRF estimation, though of the greatest interest, is still under investigation, for the problem is ill-conditioned. In this paper, we recall the most general Bayesian model for HRF estimation and show how it can beneficially be translated in terms of Bayesian graphical models, leading to 1) a clear and efficient representation of all structural and functional relationships entailed by the model, and 2) a straightforward numerical scheme to approximate the joint posterior distribution, allowing for estimation of the HRF, as well as all other model parameters. We finally apply this novel technique on both simulations and real data.
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Dates and versions

cea-00333687 , version 1 (23-10-2008)

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Guillaume Marrelec, Philippe Ciuciu, Mélanie Pélégrini-Issac, Habib Benali. Estimation of the hemodynamic response in event-related functional MRI: Bayesian networks as a framework for efficient Bayesian modeling and inference.. IEEE Transactions on Medical Imaging, 2004, 23 (8), pp.959-67. ⟨10.1109/TMI.2004.831221⟩. ⟨cea-00333687⟩
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