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Imaging and spectroscopic approaches to probe brain energy metabolism dysregulation in neurodegenerative diseases

Gilles Bonvento , Julien Valette , Julien Flament , Fanny Mochel , Emmanuel Brouillet
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (6), pp.1927-1943. ⟨10.1177/0271678X17697989⟩
Article dans une revue hal-01539753v1
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$In\ Vivo$ Calpain/Caspase Cross-talk during 3-Nitropropionic Acid-induced Striatal Degeneration

Nicolas Bizat , Jean-Michel Hermel , Sandrine Humbert , Carine Jacquard , Christophe Créminon , et al.
Journal of Biological Chemistry, 2003, 278 (44), pp.43245-43253. ⟨10.1074/jbc.M305057200⟩
Article dans une revue cea-02290633v1
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Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway

Laurene Abjean , Lucile Ben Haim , Miriam Riquelme-Perez , Pauline Gipchtein , Céline Derbois , et al.
Brain - A Journal of Neurology , 2022, ⟨10.1093/brain/awac068/6550082⟩
Article dans une revue cea-03872742v1
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Physiological synaptic activity and recognition memory require astroglial glutamine

Giselle Cheung , Danijela Bataveljic , Josien Visser , Naresh Kumar , Julien Moulard , et al.
Nature Communications, 2022, 13 (1), pp.753. ⟨10.1038/s41467-022-28331-7⟩
Article dans une revue hal-03625240v1
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ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

Florent Letronne , Geoffroy Laumet , Anne-Marie Ayral , Julien Chapuis , Florie Demiautte , et al.
EBioMedicine, 2016, 9, pp.278-292. ⟨10.1016/j.ebiom.2016.06.002⟩
Article dans une revue hal-02155738v1
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Real-Time Monitoring of Exosome Enveloped-AAV Spreading by Endomicroscopy Approach: A New Tool for Gene Delivery in the Brain

Nicola Salvatore Orefice , Benoît Souchet , Jérôme Braudeau , Sandro Alves , Françoise Piguet , et al.
Molecular Therapy - Methods and Clinical Development, 2019, 14, pp.237 - 251. ⟨10.1016/j.omtm.2019.06.005⟩
Article dans une revue cea-02997523v1
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Characterization of Mouse Lemur Brain by Anatomical, Functional and Glutamate MRI

Clément Garin
Neurons and Cognition [q-bio.NC]. Université Paris Saclay (COmUE), 2019. English. ⟨NNT : 2019SACLS174⟩
Thèse tel-02268380v1

Allele-Specific Silencing of Mutant Huntingtin in Rodent Brain and Human Stem Cells

Valérie Drouet , Marta Ruiz , Diana Zala , Maxime Feyeux , Gwennaëlle Auregan , et al.
PLoS ONE, 2014, 9 (6), pp.e99341. ⟨10.1371/journal.pone.0099341⟩
Article dans une revue hal-03272602v1

Nuclear Factor Erythroid 2-Related Factor 2 Facilitates Neuronal Glutathione Synthesis by Upregulating Neuronal Excitatory Amino Acid Transporter 3 Expression

Carole Escartin , Seok Joon Won , Carole Malgorn , Gwennaëlle Aurégan , Ari Berman , et al.
Journal of Neuroscience, 2011, 31 (20), pp.7392-7401. ⟨10.1523/JNEUROSCI.6577-10.2011⟩
Article dans une revue cea-02168419v1

Energy defects in Huntington's disease: Why “in vivo” evidence matters

Géraldine Liot , Julien Valette , Jérémy Pépin , Julien Flament , Emmanuel Brouillet
Biochemical and Biophysical Research Communications, 2017, 483 (4), pp.1084-1095. ⟨10.1016/j.bbrc.2016.09.065⟩
Article dans une revue hal-04476989v1

siRNA targeted against amyloid precursor protein impairs synaptic activity in vivo

a S Herard , L. Besret , André Dubois , J. Dauguet , T. Delzescaux , et al.
Neurobiology of Aging, 2006, 27 (12), pp.1740-1750. ⟨10.1016/j.neurobiolaging.2005.10.020⟩
Article dans une revue istex hal-02155634v1
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Possible involvement of self-defense mechanisms in the preferential vulnerability of the striatum in Huntington's disease

Laetitia Francelle , Laurie Galvan , Emmanuel Brouillet
Frontiers in Cellular Neuroscience, 2014, ⟨10.3389/fncel.2014.00295⟩
Article dans une revue hal-02459873v1

Altered activity-regulated H3K9 acetylation at TGF-beta signaling genes during egocentric memory in Huntington’s disease

Rafael Alcalá-Vida , Caroline Lotz , Baptiste Brulé , Jonathan Seguin , Charles Decraene , et al.
Progress in Neurobiology, 2022, 219, pp.102363. ⟨10.1016/j.pneurobio.2022.102363⟩
Article dans une revue hal-04312650v1
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A new statistical method to analyze Morris Water Maze data using Dirichlet distribution

Marianne Maugard , Cyrille Doux , Gilles Bonvento
F1000Research, 2019, 8, pp.1601. ⟨10.12688/f1000research.20072.2⟩
Article dans une revue hal-04445194v1
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Sulfheme formation during homocysteine S-oxygenation by catalase in cancers and neurodegenerative diseases

Dominique Padovani , Assia Hessani , Francine T. Castillo , Géraldine Liot , Mireille Andriamihaja , et al.
Nature Communications, 2016, 7, pp.1-13. ⟨10.1038/ncomms13386⟩
Article dans une revue hal-01488442v1
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Mesure de la consommation cérébrale d'oxygène par IRM du ¹⁷O : développements méthodologiques et étude de la réponse fonctionnelle chez le rongeur

Amélie Tourais
Imagerie. Université Paris-Saclay, 2023. Français. ⟨NNT : 2023UPAST116⟩
Thèse tel-04532850v1
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Upregulation of astroglial connexin 30 impairs hippocampal synaptic activity and recognition memory

Eléonore Hardy , Julien Moulard , Augustin Walter , Pascal Ezan , Alexis-Pierre Bemelmans , et al.
PLoS Biology, 2023, 21 (4), pp.e3002075. ⟨10.1371/journal.pbio.3002075⟩
Article dans une revue hal-04083283v1
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DEVEA: an interactive shiny application for Differential Expression analysis, data Visualization and Enrichment Analysis of transcriptomics data

Miriam Riquelme-Perez , Fernando Perez-Sanz , Jean-François Deleuze , Carole Escartin , Eric Bonnet , et al.
F1000Research, 2022, 11, pp.711. ⟨10.12688/f1000research.122949.1⟩
Article dans une revue cea-03872697v1

Dopamine D 1 Receptor Agonist PET Tracer Development: Assessment in Nonhuman Primates

Olivier Barret , Lei Zhang , David Alagille , Cristian Constantinescu , Christine Sandiego , et al.
Journal of Nuclear Medicine, 2021, 62 (9), pp.1307-1313. ⟨10.2967/jnumed.120.256008⟩
Article dans une revue cea-04471448v1

Quantitative validation of voxel-wise statistical analyses of autoradiographic rat brain volumes: Application to unilateral visual stimulation

Albertine Dubois , Anne-Sophie Herard , Guillaume Flandin , Edouard Duchesnay , Laurent Besret , et al.
NeuroImage, 2008, 40 (2), pp.482-494. ⟨10.1016/j.neuroimage.2007.11.054⟩
Article dans une revue istex hal-02155677v1
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Automated indexation of metabolic changes in Alzheimer's mice using a voxel-wise approach combined to an MRI-based 3D digital atlas

Jessica Lebenberg , Anne-Sophie Herard , Albertine Dubois , Marc Dhenain , Philippe Hantraye , et al.
2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010), Aug 2010, Buenos Aires, Argentina. pp.5636-5639, ⟨10.1109/IEMBS.2010.5628043⟩
Communication dans un congrès hal-02155722v1
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Metabolite diffusion up to very high b in the mouse brain in vivo: Revisiting the potential correlation between relaxation and diffusion properties

Clémence Ligneul , Marco Palombo , Julien Valette
Magnetic Resonance in Medicine, 2017, 77 (4), pp.1390-1398. ⟨10.1002/mrm.26217⟩
Article dans une revue cea-02155304v1
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Detection by voxel-wise statistical analysis of significant changes in regional cerebral glucose uptake in an APP/PS1 transgenic mouse model of Alzheimer's disease

Albertine Dubois , Anne-Sophie Herard , Benoit Delatour , Philippe Hantraye , Gilles Bonvento , et al.
NeuroImage, 2010, 51 (2), pp.586-598. ⟨10.1016/j.neuroimage.2010.02.074⟩
Article dans une revue hal-02155709v1
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The neural substrates of script knowledge deficits as revealed by a PET study in Huntington's disease.

Philippe Allain , Véronique Gaura , Luciano Fasotti , Valérie Chauviré , Adriana Prundean , et al.
Neuropsychologia, 2011, 49 (9), pp.2673-84. ⟨10.1016/j.neuropsychologia.2011.05.015⟩
Article dans une revue inserm-00624522v1

2D polarization imaging as a low-cost fluorescence method to detect α-synuclein aggregation ex vivo in models of Parkinson’s disease

Rafael Camacho , Daniela Täuber , Christian Hansen , Juanzi Shi , Luc Bousset , et al.
Communications Biology, 2018, 1 (1), ⟨10.1038/s42003-018-0156-x⟩
Article dans une revue cea-02279868v1
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A new safety index based on intrapulse monitoring of ultra-harmonic cavitation during ultrasound-induced blood-brain barrier opening procedures

Anthony Novell , Hermes A-S Kamimura , Andrea Cafarelli , Matthieu Gerstenmayer , Julien Flament , et al.
Scientific Reports, 2020, 10 (1), pp.10088. ⟨10.1038/s41598-020-66994-8⟩
Article dans une revue inserm-02888648v1
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Interaction of the chaperones alpha B-crystallin and CHIP with fibrillar alpha-synuclein: Effects on internalization by cells and identification of interacting interfaces

Maya Bendifallah , Virginie Redeker , Elodie Monsellier , Luc Bousset , Tracy Bellande , et al.
Biochemical and Biophysical Research Communications, 2020, ⟨10.1016/j.bbrc.2020.04.091⟩
Article dans une revue cea-02614589v1
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Long-chain n-3 PUFAs from fish oil enhance resting state brain glucose utilization and reduce anxiety in an adult nonhuman primate, the grey mouse lemur

Fabien Pifferi , Olène Dorieux , Christian-Alexandre Castellano , Etienne Croteau , Marie Masson , et al.
Journal of Lipid Research, 2015, 56 (8), pp.1511-1518. ⟨10.1194/jlr.M058933⟩
Article dans une revue mnhn-02291865v1
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Astrocytes réactifs et maladies cérébrales

Yiannis Poulot-Becq-Giraudon , Maria-Angeles Carrillo-de Sauvage , Carole Escartin
Médecine/Sciences, 2022, 38 (10), pp.786-794. ⟨10.1051/medsci/2022104⟩
Article dans une revue hal-03811511v1
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Fatty Acid-Binding Protein 3 is Critical for α-Synuclein Uptake and MPP+-Induced Mitochondrial Dysfunction in Cultured Dopaminergic Neurons

Ichiro Kawahata , Luc Bousset , Ronald Melki , Kohji Fukunaga
International Journal of Molecular Sciences, 2019, 20 (21), pp.5358. ⟨10.3390/ijms20215358⟩
Article dans une revue cea-02347477v1