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Delivering FLT to the Central Nervous System by Means of a Promising Targeting System: Synthesis, [11C]Radiosynthesis, and in Vivo Evaluation

 Fabienne Gourand , Mihaela-Liliana Tîntas , Axelle Henry , Méziane Ibazizène , Martine Dhilly , et al.
ACS Chemical Neuroscience, 2017, 8 (11), pp.2457-2467. ⟨10.1021/acschemneuro.7b00218⟩
Article dans une revue hal-02046279v1

Comparative Analysis between [(18)F]Fludarabine-PET and [(18)F]FDG-PET in a Murine Model of Inflammation.

 N Hovhannisyan , M Dhilly , S Guillouet , M Leporrier , Louisa Barré
Molecular Pharmaceutics, 2016, 13 (6), pp.2136-9. ⟨10.1021/acs.molpharmaceut.6b00050⟩
Article dans une revue hal-01575666v1

Evaluation of the specificity of [18F]fludarabine PET/CT in a xenograft model of follicular lymphoma: comparison with [18F]FDG and impact of rituximab therapy

 N Hovhannisyan , S Guillouet , F Fillesoye , M Dhilly , D Patin , et al.
EJNMMI Research, 2015, 5, pp.23. ⟨10.1186/s13550-015-0101-7⟩
Article dans une revue hal-01577880v1

Smoothened titania particles to improve radionuclide separation and their application to the development of a novel [68Ge]/[68Ga] generator

 D Cressier , S Oelsner , G Hunter , L Quarin , N Methot , et al.
RSC Advances, 2015, 37 (5), pp.29319-29324. ⟨10.1039/C5RA03177J⟩
Article dans une revue hal-01577767v1

Improved relapse-free survival after autologous stem cell transplantation does not translate into better quality of life in chronic lymphocytic leukemia: Lessons from the randomized European Society for Blood and Marrow Transplantation-Intergroup study

 Liesbeth de Wreede , Maggie Watson , Marleen van Os , Donald Milligan , Michel van Gelder , et al.
American Journal of Hematology, 2014, 89 (2), pp.174 - 180. ⟨10.1002/ajh.23610⟩
Article dans une revue hal-01629190v1

Chemical delivery system of metaiodobenzylguanidine (MIBG) to the central nervous system.

 Fabienne Gourand , Guillaume Mercey , Méziane Ibazizène , Olivier Tirel , Joël Henry , et al.
Journal of Medicinal Chemistry, 2010, 53 (3), pp.1281-1287. ⟨10.1021/jm901550z⟩
Article dans une revue hal-00992135v1

Hypoxia image-Guided Radiotherapy for the treatment of brain metastases from primary lung cancer, a preclinical study.

 Aurélien Corroyer-Dulmont , Samuel Valable , Jérôme Toutain , Didier Divoux , Méziane Ibazizene , et al.
3ème Congrès National d'Imagerie du Vivant (CNIV), Feb 2019, Paris, France
Communication dans un congrès hal-02200579v1
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Magnetic resonance imaging of hypoxia in acute stroke: a cross‐validation study against FMISO‐positron emission tomography

 Valable Samuel , Jérôme Toutain , Didier Divoux , Laurent Chazalviel , Aurélien Corroyer-Dulmont , et al.
NMR in Biomedicine, 2022, 36 (3), pp.e4858. ⟨10.1002/nbm.4858⟩
Article dans une revue hal-03831642v1

Cost-Effectiveness Analysis of Individualized Mycophenolate Mofetil Dosing in Kidney Transplant Patients in the APOMYGRE Trial:

 Annick Rousseau , Marie-Laure Laroche , Nicolas Venisse , Cecile Loichot-Roselmac , Alain Turcant , et al.
Transplantation, 2010, 89 (10), pp.1255-1262. ⟨10.1097/TP.0b013e3181d75952⟩
Article dans une revue hal-03134773v1
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New developments in redox chemical delivery systems by means of 1,4-dihydroquinoline-based targetor: Application to galantamine delivery to the brain

 Mihaela-Liliana Tîntas , Lénaïg Foucout , Sylvain Petit , Sylvain Oudeyer , Fabienne Gourand , et al.
European Journal of Medicinal Chemistry, 2014, 81, pp.218 - 226. ⟨10.1016/j.ejmech.2014.05.022⟩
Article dans une revue hal-03856118v1

[11C]MADAM used as a model for understanding the radiometabolism of diphenyl sulfide radioligands for positron emission tomography (PET)

 F Gourand , N Amini , Z Jia , S Stone-Elander , D Guilloteau , et al.
PLoS ONE, 2015, 10 ((9)), pp.e0137160. ⟨10.1371/journal.pone.0137160⟩
Article dans une revue hal-01587383v1

Feasibility of, and critical paths for mycophenolate mofetil Bayesian dose adjustment: Pharmacological re-appraisal of a concentration-controlled versus fixed-dose trial in renal transplant recipients

 Aurelie Prémaud , Annick Rousseau , Yannick Le Meur , Nicolas Venisse , Cecile Loichot-Roselmac , et al.
Pharmacological Research, 2010, 61 (2), pp.167 - 174. ⟨10.1016/j.phrs.2009.09.006⟩
Article dans une revue istex hal-03134625v1
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[18F]Fludarabine-PET in a murine model of multiple myeloma

 N Hovhannisyan , M Dhilly , M Fidalgo , F Fillesoye , S Guillouet , et al.
PLoS ONE, 2017, 12 (5), pp.e0177125. ⟨10.1371/journal.pone.0177125⟩
Article dans une revue hal-01575068v1

18 F-Fludarabine PET for Lymphoma Imaging: First-in-Humans Study on DLBCL and CLL Patients

 Sylvain Chantepie , Narinée Hovhannisyan , Stéphane Guillouet , Jean-Pierre J.-P. Pelage , Méziane Ibazizene , et al.
Journal of Nuclear Medicine, 2018, 59 (9), pp.1380-1385. ⟨10.2967/jnumed.117.206920⟩
Article dans une revue hal-02006592v1

N-[18F]-FluoropropylJDTic for κ-opioid receptor PET imaging : Radiosynthesis, pre-clinical evaluation, and metabolic investigation in comparison with parent JDTic.

 S Schmitt , J Delamare , O Tirel , F Fillesoye , M Dhilly , et al.
Nuclear Medicine and Biology, 2017, 44, pp.50-61. ⟨10.1016/j.nucmedbio.2016.09.005⟩
Article dans une revue hal-01575523v1
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Simultaneous mapping of vasculature, hypoxia and proliferation using DSC-MRI, 18F-FMISO PET, and 18F-FLT PET in relation to contrast enhancement in newly diagnosed glioblastoma

 Solène Collet , Jean Sébastien Guillamo , David Hassanein Berro , Ararat Chakhoyan , Jean-Marc Constans , et al.
Journal of Nuclear Medicine, 2021, 62 (10), pp.1349-1356. ⟨10.2967/jnumed.120.249524⟩
Article dans une revue hal-03123047v1

Synthesis and in vitro characterization of trans- and cis-[18F]-4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]-3-fluoropiperidine-1-carboxylates as new potential PET radiotracer candidates for the NR2B subtype N-methyl-d-aspartate receptor

 Radouane Koudih , Gwénaëlle Gilbert , Martine Dhilly , Ahmed Abbas , Louisa Barre , et al.
European Journal of Medicinal Chemistry, 2012, 53, pp.408 - 415. ⟨10.1016/j.ejmech.2012.04.011⟩
Article dans une revue istex hal-01853609v1

Simultaneous tritium labelling of two potent 5-HT4 ligands

 Franck Sobrio , Stéphane Lemaitre , Antoine Hinsberger , Louisa Barre , Bernard Rousseau , et al.
European Journal of Medicinal Chemistry, 2010, 45 (3), pp.1263-1265
Article dans une revue hal-02045952v1

2-[18F]Fludarabine, a Novel Positron Emission Tomography (PET) Tracer for Imaging Lymphoma: a Micro-PET Study in Murine Models

 Martine Dhilly , Stéphane Guillouet , Delphine Patin , Fabien Fillesoye , Ahmed Abbas , et al.
Molecular Imaging and Biology, 2014, 16 (1), pp.118 - 126. ⟨10.1007/s11307-013-0659-2⟩
Article dans une revue hal-01599730v1

Novel fluoroalkyl derivatives of selective kappa opioid receptor antagonist JDTic: Design, synthesis, pharmacology and molecular modeling studies.

 S Schmitt , N Colloc'H , C Perrio
European Journal of Medicinal Chemistry, 2015, 90, pp.742-50. ⟨10.1016/j.ejmech.2014.12.016⟩
Article dans une revue hal-01576209v1

StO2-MRI sensitively images the ischemic brain: a comparison to MRI perfusion/diffusion mismatch and [18F]-FMISO-PET

 S Valable , J Toutain , D Divoux , L Chazalviel , A Corroyer-Dulmont , et al.
28th International Symposium on Cerebral Blood Flow, Metabolism and Function & 13th International Conference on Quantification of Brain Function with PET, Apr 2017, Berlin, Germany. Journal of Cerebral Blood Flow and Metabolism, 37, S1, pp.219
Poster de conférence hal-02265365v1

Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

 D Cressier , M Dhilly , Tt Cao Pham , F Fillesoye , F Gourand , et al.
Molecular Imaging and Biology, 2016, 18 (3), pp.334-43. ⟨10.1007/s11307-015-0906-9⟩
Article dans une revue hal-01575680v1

[ 18 F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [ 18 F]FDG in human xenograft models

 Narinée Hovhannisyan , Fabien Fillesoye , Stéphane Guillouet , Méziane Ibazizene , Jérôme Toutain , et al.
Theranostics, 2018, 8 (16), pp.4563-4573. ⟨10.7150/thno.26754⟩
Article dans une revue hal-02006576v1
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ZAP-70 intron1 DNA methylation status: Determination by pyrosequencing in B chronic lymphocytic leukemia

 Sylvain Chantepie , Dominique Vaur , Christoph Grunau , Véronique Salaün , Mélanie Briand , et al.
Leukemia Research, 2010, 34 (6), pp.800-808. ⟨10.1016/j.leukres.2009.10.018⟩
Article dans une revue istex hal-02358614v1
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Evaluation of Specific Binding of [11C]RTI-97 to KOR by Autoradiog-raphy and PET Imaging in Rat

 Fabien Fillesoye , Méziane Ibazizene , Nicolas Marie , Florence Noble , Cécile Perrio
ACS Medicinal Chemistry Letters, 2021, 12 (11), pp.1739-1744. ⟨10.1021/acsmedchemlett.1c00369⟩
Article dans une revue hal-03381883v1

FMISO-PET-derived brain oxygen tension maps: application to glioblastoma and less aggressive gliomas

 Ararat Chakhoyan , Jean-Sébastien Guillamo , Solène Collet , François Kauffmann , Nicolas Delcroix , et al.
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-08646-y⟩
Article dans une revue hal-02043459v1

[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis.

 L Bekaert , S Valable , E Lechapt-Zalcman , K Ponte , S Collet , et al.
European Journal of Nuclear Medicine and Molecular Imaging, 2017, 44 (8), pp.1383-1392. ⟨10.1007/s00259-017-3677-5⟩
Article dans une revue hal-01575007v1

Dihydroquinoline Carbamate Derivatives as "Bio-oxidizable" Prodrugs for Brain Delivery of Acetylcholinesterase Inhibitors: [¹¹C] Radiosynthesis and Biological Evaluation

 Pierre Bohn , F. Gourand , Cyril Papamicaël , M. Ibazizène , M Dhilly , et al.
ACS Chemical Neuroscience, 2015, 6 (5), pp.737-744. ⟨10.1021/cn5003539⟩
Article dans une revue hal-01578046v1

Imaging of brain oxygenation with magnetic resonance imaging : A validation with positron emission tomography in the healthy and tumoural brain.

 S Valable , A Corroyer-Dulmont , A Chakhoyan , L Durand , J Toutain , et al.
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (7), pp.2584-2597. ⟨10.1177/0271678X16671965⟩
Article dans une revue hal-01575065v1

Radiolabelling of 1,4-disubstituted 3-[18F]fluoropiperidines and its application to new radiotracers for NR2B NMDA receptor visualization

 Radouane Koudih , Gwénaëlle Gilbert , Martine Dhilly , Ahmed Abbas , Louisa Barre , et al.
Organic & Biomolecular Chemistry, 2012, 10 (42), ⟨10.1039/c2ob26378e⟩
Article dans une revue hal-01853954v1
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